This module provides an overview of genetic epidemiology with a focus on design, analysis and interpretation in studies of complex disease. It is meant as an introduction to the field with a focus on surveying the various methods for discovering how genetic factors influence health and disease.

The module discusses classic genetic epidemiology methods and study designs, including twin studies, family studies, segregation analysis, linkage analysis and population-based association studies, as well as more contemporary topics including gene-environment interactions, rare variant analysis and precision medicine applications. These topics will be reinforced through in-class exercises along with critical reading and discussion of recent publications.